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Animal studies in pigs at doses up to 1.1 mg/kg showed no adverse effects

PubMed search Multi-pathway tissue-repair research combination protocols exploring whether dual-pathway coverage produces additive or synergistic regenerative effects

The research comprised placebo and control cohorts

doi: 10.1016/j.biomaterials.2015.11.060 157 LiuY.HuangR.HanL.KeW.ShaoK.YeL.et al

Alexander Weber, an orthopedic surgeon and chief of sports medicine at the University of Southern California who has published a review of the evidence