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Cell 17 , 341350 (2005)

Notably, TLCA enhanced T cell activation and anti-tumor immunity, suggesting its potential to favorably modulate the TIME and act as an ICI adjuvant ( Eubacterium spp

However, oral supplementation of L-arginine, the precursor for NO synthesis, has been shown to be largely ineffective at increasing NO synthesis and/or bioavailability for several reasons, which makes L-citrulline much more ideal for boosting levels of L-arginine and subsequently NO

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