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In that stretch, at least three more papers piled onto the mouse data [1][2], a 2021 review took stock of the field and said, plainly, clinical trials targeting NNMT have not been reported until now [4]

While individual responses vary, some patients report fewer or different side effects compared to injectable weight loss medications

Over the years, it has been studied for obesity, metabolic disorders, and fat loss, and it is now used in wellness and performance clinics as a research peptide

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Critically, two of the efficacy studies were long-term investigations extending up to 24 weeks, providing meaningful data on sustained exposure safety