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Advise females of reproductive potential to use effective contraception during XENPOZYME treatment and for 14 days after the last dose if XENPOZYME is discontinued

References: Julius M, Lang CA, Gleiberman L, Harburg E, DiFranceisco W, Schork A

Furthermore, the extent of this accumulation tightly parallels the dismantling of synapses and the demise of nerve cells in AD patients (Rajmohan and Reddy, 2017)