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When to absolutely discard expired medication Certain situations demand immediate disposal regardless of how close to or past the BUD: Any visible cloudiness, particles, or color change Vial was frozen at any point Extended exposure to temperatures above 30C (86F) More than 21 cumulative days at room temperature Unusual smell from the vial More than 7 days past the assigned BUD For comparison, the same principles apply to using expired semaglutide and other compounded GLP-1 medications

Remember heat always moves from hot to cold, and as the brine is colder than the surface it removes the heat

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Avoid twisting while lifting