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Description

However, this effect appears to be overcome by longerterm training, with Yfanti et al

reported that combined treatment of CUR and sunitinib increased the expression of the ADAMTS18 gene and significantly decreased the expression level of NCOA4, FTH1 and p53, indicating that CUR could lower the mRNA and protein expression levels of NCOA4, FTH1, and P53, which suggested that CUR may drive ferroptosis by increasing ADAMTS18 gene expression (111)

Increased range of motion and mobility

A randomized controlled trial indicated that curcumin supplementation resulted in significant improvements in liver enzyme levels and histological features of liver steatosis among patients with NAFLD, underscoring its therapeutic potential