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Because KLRG1 is widely used as a marker of highly activated, cytokine-producing ILC2s (66, 67), this finding supports the idea that melatonin drives a phenotypic transition from an activated, KLRG1 high effector state toward a more quiescent, KLRG1 low phenotype

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Gastroenterology 133 , 507516 (2007)

Honda, Y., Takaomi Kessoku, Sumida, Y., Kobayashi, T., Kato, T., Ogawa, Y., Wataru Tomeno, Kento Imajo, Fujita, K., Yoneda, M., Kataoka, K., Masataka Taguri, Yamanaka, T., Seko, Y., Tanaka, S., Saito, S., Ono, M., Satoshi Oeda, Eguchi, Y., & Wataru Aoi