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There are at least three ways to decrease influence receptors Decrease total androgen production Decrease androgen receptor expression Block androgen receptors Lets dive into all three

Pellerin L, Magistretti PJ

Mtb PhoP may regulate the expression of more than 110 genes [307], especially those related to lipid biosynthesis [307, 314]

A genetic cause/predisposition still remains unclear in most of ALS cases (~ 80%), and SOD1 mutations describe only approximately 3% of total ALS cases (called SOD1 -ALS) [4]