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This work was supported by grants from Centre National de la Recherche Scientifique (CNRS), Aix-Marseille Universit, the A*MIDEX initiative and Fondation Recherche Mdicale to F.B., and by the European Research Council (FP7/20072013) ERC independent researcher starting grant (282335Sulfenic), the WELBIO and by grants from the F.R.S.-FNRS to J.F.C

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