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Edited by Professor Anastasis Stephanou Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made

Park et al., 2017)

The synergistic interaction of chemicals combined with natural stressors, such as pathogens, has been studied in aquatic organisms, such as Daphnia and Artemia 30, 35 , and, more recently, in the honey bee 36,37,38,39,40,41,42,43

Clinical trials have been conducted on mice using tomatoes expressing antibodies or proteins that stimulate antibody production targeted to norovirus, hepatitis B, rabies, HIV, and respiratory syncytial viruses and anthrax bacteria

doi: 10.1016/j.biomaterials.2018.06.007 186 ChenHTianJHeWGuoZ