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Syst 13, 218227 (2008)

Description Research Overview GHK is an endogenous tripeptide that forms a stable high-affinity complex with Cu(II), yielding GHK-Cu, a well-characterized ligand-metal pair.[1,2] In research settings, GHK-Cu serves as a model for copper delivery and signaling, enabling investigation of matrix protein synthesis, metalloproteinase regulation, antioxidant responses, and transcriptional reprogramming under standardized conditions.[3,4] Its versatility has made it a reference tool in dermatologic, regenerative, and oxidative stress research

Subarachnoid injection of Ab against H2 ligand binding site of GluR delta elicited ataxic symptoms in mice and blocked the induction of LTD in cultured PCs [58]

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