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Clinical Cancer Research, 22 (8), 20742082

3.4 PCs inhibit pigmentation in aging skin UV radiation is the primary inducer of melanin production

Raw data from the CRISPR knockout screen are in Supplementary Table 2

CJC-1295 DAC: the long-acting GHRH The DAC (Drug Affinity Complex) modification extends the half-life to roughly 8 days, radically changing the paradigm: instead of a daily pulse, CJC-1295 DAC installs a near-continuous GHRH signal