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Whether the causal factor is genetic or otherwise, what remains clear is that there is underlying inflammation that causes excess keratin production, which accumulates and blocks the follicles, resulting in a characteristic rash caused by the formation of these little plugs

Regulation of neuronal chloride homeostasis by pro- and mature brain-derived neurotrophic factor (BDNF) via KCC2 cationchloride cotransporters in rat cortical neurons

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An open-label, investigator-initiated, single-center, prospective, pilot clinical study to evaluate the efficacy of a skin whitening serum applied twice daily combined with a spot-preventing SPF50+ sunscreen in healthy female subjects with melasma hyperpigmentation