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Treatment for diabetic peripheral neuropathy: what have we learned from animal models

Melatonin is also antiestrogenic and antioxidant

doi: 50

190 Hyperuricemia and diseases An elevated uric acid concentration above physiological levels can pose a potential risk factor for several diseases closely associated with metabolic disorders

These nerve fibers release neuropeptides that trigger the production of inflammatory mediators such as cytokines, and prostaglandins, which activate nociceptive pathways (174)