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All other data were analyzed with an ANOVA followed by a Tukeys post-hoc test

Nanomaterials enable precise tumor targeting, significantly enhancing local drug accumulation

Melatonin alone had no effect, and there was little interaction between IF and melatonin except for their effects on adipocyte area and number, the abundance of Bacteroidetes and Akkermansia , and the intestinal metabolites alanine, valine and isoleucine