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Description

J., Bauer, C

High-resolution crystal structure of aldose reductase complexed with the novel sulfony-pyridazinone inhibitor exhibiting an alternative active site anchoring group

These findings suggest an age-associated alteration in erythropoiesis, suggesting that a shortened RBC lifespan in older adults may enhance erythropoietic activity and the release of larger, younger erythrocytes leading to increasing MCV values over time