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[DOI] [PubMed] [Google Scholar] 53.Jiang H., Tian X., Guo Y., Duan W., Bu H., Li C

Indeed, since proteolytic enzymes prefer the natural L-configuration rather than the D-one, it is well-documented that replacing L-amino acids with their D-enantiomers, incorporating methylated amino acids, or introducing -amino acids and peptoid residues are among the usual approaches to prolonging the plasma half-life

Hypoxia also inhibits mTORC1 via the actions of Redd1/RTP801, which was first discovered in Drosophila as Scylla and Charybdis