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[3] At the 12 mg dose, the mean weight reduction was about 17.5% at 24 weeks (the primary endpoint) rising to roughly 24.2% at 48 weeks , compared with about 2.1% for placebo

It raises decorin levels by 302%, a proteoglycan that organizes collagen into stable, functional structures

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To induce superovulation, mice were injected intraperitoneally with 10 IU of pregnant mare serum gonadotropin (PMSG), followed 48 hours later by 10 IU of human chorionic gonadotropin (hCG)