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Description

Inhibition of substance P/NK-1R interactions using the non-peptide NK-1R antagonist RP-67580 reduces the inflammatory response and the reactive astrogliosis associated with Trypanosoma brucei brucei infection of the CNS (Kennedy et al., 1997), further supporting a role for substance P/NK-1R interactions in neuroinflammation associated with eukaryotic parasite CNS infections

2025 Apr 15:S0891-5849(25)00231-X

It is intended solely for in vitro testing and laboratory experimentation

CD157: from immunoregulatory protein to potential therapeutic target

3.4.4.2 Prebiotics In a male rat model of PTSD-like symptoms induced via amygdala hyperactivation (a key pathophysiological mechanism of PTSD)3 weeks of treatment with the prebiotic GOS restored microbial homeostasis by enriching beneficial Bifidobacterium animalis and Limosilactobacillus reuteri , while eliminating harmful Enterococcus casseliflavus (Ruciski et al., 2025)