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The Bcl-2 family, comprising both anti-apoptotic proteins (like Bcl-2 and Bcl-xl) and pro-apoptotic proteins (like Bax and Bak), governs apoptosis primarily by modulating mitochondrial permeability

Characterized by its insidious onset, poor prognosis and limited treatment options, initial prevention of lesions in DR carries profound clinical and societal significance, before visual symptoms become irreversible

For GSSG determination, the cell extracts were treated with 4-vinyl pyridine (Sigma-Aldrich) for GSH derivatization, and the excess of 4-vinyl pyridine was neutralized with triethanolamine

But the short answer is no