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Regular maintenance sessions are necessary to sustain the effects, with the frequency customised based on individual needs and how well the treatment works [4]

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In COPD, CT-detected mucus plugging identifies patients at increased risk of exacerbations, lung function decline, and mortality, including a substantial subgroup without chronic cough or sputum production [10]

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doi:10.1016/S0014-5793(01)03302-6