Abbreviations ACTH: adrenocorticotropic hormone CF: chronic fatigue CFS: chronic fatigue syndrome CMI: cell-mediated immune CNS: central nervous system CRH: corticotropin-releasing hormone CVD: cardiovascular disease DISC1: disrupted-in-schizophrenia 1 EBV: Epstein-Barr virus HHV: human herpesvirus HPA: hypothalamic-pituitary-adrenal IBS: irritable bowel syndrome IL: interleukin IL-1RA: IL-1 receptor antagonist LPS: lipopolysaccharide MDA: malondialdehyde ME: myalgic encephalomyelitis NF: nuclear factor O&NS: oxidative and nitrosative stress PEM: post-exertion malaise lasting more than 24 h PGs: prostaglandins PUFAs: polyunsaturated fatty acids RNS: reactive nitrogen species ROS: reactive oxygen species SF-36: 36-item short-form health survey SNS: sympathetic nervous system TDO: tryptophan 2,3-dioxygenase TGF: transforming growth factor Th: T helper TNF: tumor necrosis factor
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Our work explores the synergistic combination of L-carnosine and copper, yielding nanoclusters (CuL) that show: Enhanced cytotoxicity toward lung cancer cells (A549) Minimal toxicity to normal cells Nanomolar-level sensitivity for glutathione detection Strong potential for theranostic applications Grateful to my co-authors, collaborators, mentors, Netaji Subhas University of Technology (NSUT, Formerly NSIT), the Indian patent office, the patent agent, and the editorial team for their support throughout this journey
