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Some caution is recommended, however, due to the limitations of current research as well as indications that many nutrients exert biphasic, dose-dependent effects and that genetic polymorphisms may alter outcomes

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In 1971, it was reported that, in the presence of excess GSH, one molecule of CSSSC led to the reduction of at least 25 molecules of cytochrome c, implicating hydropersulfides as catalysts 30