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A recent study discovered that Schisandrin B may alleviate the occurrence and development of NAFLD by modulating signaling pathways such as PPAR, perilipin 2, phosphoenolpyruvate carboxykinase 1, ATP citrate lyase, and fatty acid desaturase 1, increasing the abundance of beneficial bacteria like Alloprevotella and Lachnospiraceae_NK4A136_group, and simultaneously increasing the expression of ZO-1 and Occludin proteins to improve intestinal barrier damage [147]

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