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They also suggested that the alteration in brain connectivity between these networks may shift the balance between network integration and segregation at the whole-brain level, necessitating the effective treatment strategies achieving the efficient neuronal communication (60)

And then importantly balance

When more free radicals than antioxidants are present, oxidative cell damage occurs

B12 injections can dramatically improve energy levels, enhance mood, support cognitive function, and contribute to overall physical health by directly addressing B12 deficiency or optimizing B12 levels for health maintenance

While we have shown that ES-Cu can enhance NFE2L2 protein stability, further investigations are required to ascertain whether sequestosome 1 (SQSTM1, a selective autophagy receptor that assists in targeting specific cellular components) mediates KEAP1 degradation 25 , contributing to the regulation of NFE2L2 protein stability during cuproptosis, as observed in response to ferroptotic cell death 17