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Like all proteins, FBP is heat-sensitive, and denaturation affects its folate binding capacity

[cited 2021 Feb 6]

For a Part D rebatable drug first approved or licensed on or before October 1, 2021, section 1860D-14B(b)(4) of the Act specifies that the benchmark period manufacturer price is the sum of the products for each calendar quarter of the payment amount benchmark period (that is, January 1, 2021, through September 30, 2021) of (1) the AMP for the Part D rebatable drug reported for the calendar quarter), and (2) the total units reported for the corresponding calendar quarters divided by the total units of the Part D rebatable drug reported for the 3 calendar quarters in the payment amount benchmark period

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