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Description

Mech Ageing Dev 2008

The variance components were used to simulate 1000 data sets, with the 25 % effect size in the senior group

The LOD and limit of quantification (LOQ) were calculated mathematically by the relationship between the standard error () of the calibration curve and its slope (S) using the multiplier according to ICH [50]ICH Q2 (R1), Validation of analytical procedures: text and methodology, in Proceedings of the International Conference on Harmonization, Geneva, Switzerland, 2005