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This bidirectional crosstalk establishes self-amplifying feedback loops that exacerbate neurodegeneration, promote demyelination, and remodel the tumor microenvironment, thereby positioning ferroptosis as both a mechanistic driver and a disease amplifier across diverse CNS pathologies

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doi: 10.4049/jimmunol.178.12.7516 74 FearonUCanavanMBinieckaMVealeDJ