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in protein detection experiments, such as western blot and immunofluorescence, n 3

That is a genetic-knockdown study in mice, not a drug trial: it tells you the target is real and metabolically meaningful in an animal model, but it does not test a drug, a dose, or a route

531 More accurate studies of morphology of astrocytes in aged mice in situ using intracellular injections of fluorescent dye Alexa Fluor 594 with subsequent two-photon imaging and 3D reconstruction identified a substantial reduction of astrocytic size and complexity with particular degradation of perisynaptic leaflets (Fig

172 Wnt/-catenin pathway in liver disease The liver is a metabolic factory in humans

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