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Jingguo Wu, [email protected] These authors have contributed equally to this work This article was submitted to Biosensors and Biomolecular Electronics, a section of the journal Frontiers in Bioengineering and Biotechnology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Heterozygous missense Onset age: 18 to 39 years Sensory neuropathy: Axonal No ophthalmoplegia Also see Ataxic sensory neuropathy, Sporadic PEO, Recessive SANDO, dominant: Twinkle mutations MELAS Alpers syndrome PEO + Myopathy & Respiratory failure (MTDPS11) 154 Mitochondrial genome maintenance exonuclease 1 (MGME1

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