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These include steroids, antiviral drug Remdesivir (RDV), and monoclonal antibody (mAb) ( Molnupiravir as early treatment has shown a reduced risk of hospitalization or death in at-risk, unvaccinated adults with Covid-19 ( Pfizer released phase 2/3 results from the PAXLOVID trial, confirming the novel COVID-19 oral antiviral treatments robust efficacy in reducing the risk of hospitalization or death by 89% (within 3 days of symptom onset) and 88% (within 5 days of symptom onset) compared to placebo

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Chem Eng J 428:131006

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SUMO is a posttranslational modification that is covalently added to lysine residues on other proteins (Figure 5)

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