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doi: 10.1136/gut.6.5.472

Also, mitochondrial dysfunction such as morphological alterations, electrolyte imbalance, and reactive oxygen species (ROS) generation has been considered an important element in PIPN

While these interactions do not establish direct causality, they provide integrative evidence linking metabolomic alterations to gene networks previously implicated in neurodevelopmental and metabolic regulation

In adipose models, reduced NNMT activity has been linked with smaller adipocyte size and diminished fat depots, suggesting a potential role for this inhibitor in fat mass modulation under research conditions

Vitamin B12 Vitamin B12 supports the production of red blood cells, which are responsible for delivering oxygen and nutrients throughout your body