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The laboratory mouse models are divided into xenograft models, chemically and/or diet- and virus-induced, and genetically modified models (GEMs) [193, 197199]

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Zhang J, Jia P-P, Liu Q-L, Cong M-H, Gao Y, Shi H-P, et al

Appetite Regulation & Craving Reduction Certain peptides act on the hypothalamus to modulate satiety and hunger signaling

43 Similarly, miR-31 directly inhibits the negative regulatory factors of Wnt, namely, DKK1, GSK3, and AXIN1, to stimulate canonical Wnt signalling