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The semaglutide titration continues with 0.5mg weekly for 4 weeks, then 1.0mg weekly for 4 weeks, followed by 1.7mg weekly for 4 weeks, and finally reaching the target dose of 2.4mg weekly if tolerated

The endocrinologist or prescribing physician manages the indication for treatment, dose escalation, metabolic response, systemic side effects and long-term safety

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This pioneering treatment was first reported in The Lancet medical journal in June 1832, and since then intravenous (IV) fluid replacement therapy has become commonplace in hospitals for the severely sick who cannot take fluids orally for various reasons