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2022;83:21m14345

This may be attributed to the role of metformin in reducing the production of sFlt-1 and soluble endoglin by endothelial cells, trophoblasts, and syncytiotrophoblasts, and modulating anti-angiogenic factors at the mitochondrial level (Romero et al., 2017)

A systematic review and meta-analysis study conducted by Ebrahimi et al

Its a promising option for biohackers and anyone serious about staying ahead of aging

Additionally, endothelin 1, a vasoconstrictor peptide synthesized by the endothelium, plays a crucial role in maintaining vascular tone in healthy individuals