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Curcumin was well-tolerated, had no adverse effects, and exerted an anti-rheumatic activity identical to that of phenylbutazone as shown by improvement in joint swelling, morning stiffness, and walking time

2009;89(5):1488S-1493S

All animal experiments in this study were performed in strict accordance with the institutionally approved protocol according to the USPHS Guide for the Care and Use of Laboratory Animals and with the approval of the Institutional Animal Care and Use Committee of the South China University of Technology

However, optimal dosage varies on the person because everyones L-carnitine stores contain different amounts

Biomaterials 167 , 132142 (2018)