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Tirzepatide is a dual-action medication known as a GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptor agonist

59 In a crossover trial in 40 patients with primary open-angle glaucoma or normal tension glaucoma being treated with a topical prostaglandin analog, IOP decreased and tests of retinal function improved after supplementation with 600 mg PEA daily in addition to topical treatment for four months

To minimize the risk of liver damage, it is crucial to adhere to the recommended dosage and avoid exceeding the maximum daily limit

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Methods: Female wild-type (WT) and Has1,Has3 double knockout ( Has1,3 dko) mice were aged to 7 weeks (young) or 17 months (old) and fed normal mouse chow (5% calories from fat)