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10.1 Pharmacological therapy Pharmacological treatment remains central, acting on multiple mechanistic pathways relevant to disease progression

Leveraging from the transdermal microneedle field, an orally-administered robotic pill was developed by Rani Therapeutics (USA) in which sucrose-based needles were activated from a capsule following an osmotic gas-driven swelling

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Am J Physiol Endocrinol Metab 288:E115 Straub SG, Sharp GW (2004) Hypothesis: one rate-limiting step controls the magnitude of both phases of glucose-stimulated insulin secretion