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The gut-joint axis: microbial dysbiosis and OA Emerging evidence firmly establishes a link between gut microbiota dysbiosis and OA progression, primarily mediated by microbial metabolites via the gut-joint axis. The core protective mechanism involves short-chain fatty acids (SCFAs) like butyrate and propionate, produced from dietary fiber fermentation by commensals such as Bacteroides and Faecalibacterium prausnitzii

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both are prescription-grade or trial-grade agents, and any material bought outside those channels is of unverified identity and purity regardless of what the trials showed

When NNMT is too active, it consumes our precious supply of NAD+ (nicotinamide adenine dinucleotide), a coenzyme that is absolutely essential for cellular energy production and DNA repair