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Gum Arabic in combination with IFN- promotes the M1 polarization in macrophage

Regulation of metallothionein gene expression by oxidative stress and metal ions

10.1002/cne.21823 204 MatsumotoM.HatakeyamaT.MorimotoK.YanagiharaT

PMID: 37 ZhengQMaksimovicIUpadADavidY

In addition, TAMs contribute to the immunosuppressive tumor microenvironment by secreting anti-inflammatory signals that prevent other components of the immune system from recognizing and attacking the tumor