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However, the key limitation is the lack of long-term human safety data

the AngIV Analog D-Nle-Tyr-Ile-NH(CH 2 ) 5 CONH 2 is More Metabolically Stable than Norleual (Nle-Tyr-Leu- -(CH 2 NH 2 ) 3-4 -His-Pro-Phe (SEQ ID NO: 1): AngIV-related peptidomimetic Norleual was previously shown to possess, anti-HGF/Met, anti-angiogenic, and anti-cancer activities (Yamamoto et al., 2010)

Accessed January 27th, 2023

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