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The amount of cytochrome c oxidase negative muscle fibers in treated mice decreased by 30%, the citrate synthase activity in muscle as a marker of mitochondrial biogenesis was doubled, liver lipid levels were restored and muscle mitochondrial ultrastructure was normalized (no ragged red fiber-like muscle fibers or mitochondria with distorted structure and cristae on electron microscopy)

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Multiple graft materials have been used, including dermis, cadaveric fascia, cadaveric pericardium, saphenous vein, and intestinal submucosa

Characterization of TMAO productivity phenotypes by using OCCT may also help explore key human microbiome signatures of TMA synthesis from carnitine [11]