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Therefore, developing therapeutic techniques (Table 1) to promote endogenous neurogenesis to repair neurological deficits after neonatal HIBD is an urgent priority

C.DaunizeauJ.FlandinG.FristonK.et al

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Unlike traditional inhibitors, which merely block protein activity, PROTACs remove the protein entirely, conferring several distinct advantages: (1) Complete Protein Removal: Eliminates the target protein entirely, preventing compensatory mechanisms and overcoming resistance associated with target overexpression

A subgroup of individuals with autism may show evidence of mitochondrial stress or altered energy metabolism