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Vial Integrity: Extreme conditions can affect the glass or plastic of the vial and the rubber stopper, potentially leading to micro-cracks, leaks, or changes in the stoppers sealing ability

Refrigeration slows degradation even fruther

The small molecule idebenone also has potential to treat Friedreichs ataxia

The only exception is the mitochondria present in the heart of rat.33 This implies that the breakdown of hydrogen peroxide to water and oxygen is carried out by another enzyme known as glutathione peroxidase in mammalian cell mitochondria

It should be stressed that in encephalopathy associated with liver disease, other factors may contribute to the central nervous system dysfunction in addition to hyperammonemia