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Description

Hence, L-lactate metabolism in mitochondria is likely to produce partial ROS and then activate its related signals if there exists analogous oxidase located at the mitochondrial inner membrane in the neurons

Author Contributions Concept and design: Eunhee Choi Acquisition, analysis, or interpretation of data: Eunhee Choi, Laverne Yip, Krishna Kishore Anna, Gabriela Galicia Garcia, Maria F

This study was approved by the Ethic Committee of School of Medicine, University of Zagreb (Project code: 380-59-10106-17-1001290

The review was conducted under Project Orbis, the FDAs framework for concurrent international oncology review, alongside partner agencies from Australia, Brazil, Canada, Singapore, and Switzerland