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Positive results for these antibodies, along with a serum cobalamin level of less than 200 ng/L, confirm the diagnosis for pernicious anemia

10.1038/s41569-020-0339-2 57 TaoL.HuangX.XuM.QinZ.ZhangF.HuaF.et al (2020)

Synthetic B12 allows medical professionals to efficiently supplement in people with a deficiency, a difficulty absorbing B12 through food, or with underlying conditions that impact B12 absorption