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Methods: This study enrolled 1735 HBeAg-negative non-cirrhotic patients without antiviral therapy who had been followed up for at least 1 year and whose baseline HBcrAg levels could be measured by iTACT-HBcrAg

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Images and radiance were acquired 10 min after intraperitoneal injection of 150 l of 100 mg/kg D-luciferin (BioVision Inc., Waltham, MA, USA) in sterile PBS

After consideration of public comments, we are finalizing our proposal to adopt a new cost measure exclusion policy, with modification