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Furthermore, the combination of silibinin with paclitaxel or metformin enhances anti-cancer effects in lung cancer (A549) in vitro and in vivo by increasing chemotherapy sensitivity, modulating the tumor microenvironment, and effectively inducing apoptosis [931, 934, 935]

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[DOI] [PubMed] [Google Scholar] 18.Moiz A., Filion K.B., Tsoukas M.A., Yu O.H., Peters T.M., Eisenberg M.J

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The oxidation resistance indicator reduced glutathione/oxidized glutathine (GSH/GSSG) was significantly decreased in the D + ND group compared to that in the ND group, whereas it was significantly increased in the D + MS group compared to that in the D + ND group (Fig

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