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Table 2 Spearman correlation analysis between gut microbiota-derived metabolites and biochemical indexes

PM 2.5 induces oxidation-dependent nuclear NF-B activation, which promotes the release of proinflammatory cytokines IL-6, IL-8, and TNF- in the intestine

Notably, heatmap showing the expressions of significantly expressed genes from the pathways of interest was generated by the R package ggplot2 using the metric FPKM, and was colored by the z-score that was computed from the average FPKM of samples in each stage by subtracting the value of the average FPKM in the four stages then dividing by the standard deviation

GSK is also evaluating the vaccine for use in people 18-49 at increased risk of severe disease, and immunocompromised patients 18 and older