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[ref] Autoimmune diseases vary widely in the immune response, and MS may be an outlier in responding negatively to increasing BH4

CL is synthesized in the mitochondrial inner membrane, or IM, and a fraction of CL is transported to the OM

doi: 10.1210/jc.2013-2374 8 JiaLYFengJXLiJLLiuFYXieLZLuoSJet al

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Membrane protein extraction: Using the Membrane and Cytosol Protein Extraction Kit (Beyotime, P0033), add Membrane Protein Extraction Reagent A to the rice protoplasts and homogenize on ice with 30-50 strokes to disrupt the cells